Jane Villanueva (Gina Rodriguez) is a driven young woman studying to become a teacher, nursing a dream to be a writer, and supporting herself with a job at a hot new Miami hotel. All of Jane's meticulous life plans are turned upside down, however, when she sees her doctor for a routine check-up and is accidentally artificially inseminated with a specimen meant for someone else. Now, Jane is faced with the most important decisions of her life - a life that has suddenly become as dramatic, complicated and unpredictable as the telenovelas she has always loved
Jane struggles to keep her unexpected pregnancy from taking over her life, but with her mom Xiomara pressuring her to sue the doctor who accidently inseminated her, and her constant run-ins with the baby's biological father, Rafael, life is anything but normal. To top it off, Michael's jealousy about Jane and Rafael's past leads him to make an unexpected alliance with Petra. Meanwhile, Jane's own father, Rogelio, is insisting on meeting his daughter, but Xiomara wants to keep the secret from Jane a little while longer.
Jane considers making a life-changing decision about her and Michael’s relationship. Alba is disappointed in Xo’s handling of Rogelio, so Alba takes it into her own hands to stop Rogelio from trying to see Jane. Meanwhile, Jane continues to question whether Petra will be a fit mother, and her pursuit of the truth leads to an unexpected change in their relationship. Michael’s on-going murder investigation leads to an unexpected discovery.
In addition to being overwhelmed with all the wedding planning, Jane begins to feel guilty about her emerging feelings towards Rafael and decides to tell Michael during their pre-wedding counseling. Elsewhere, Rafael and Petra are faced with someone from their past and neither are happy about it. Meanwhile, Rogelio learns about Jane's impending nuptials and pushes Xo to let him be part of his daughter's wedding.
Jane moves in with Michael after she gets mad at Xo, but then she reconsiders her hasty actions. Meanwhile, Rogelio grows anxious when Jane plans to meet with him; and Rafael and Petra continue to have marital problems.
Jane bonds with Rogelio until she meets his stepdaughters, who aren't very nice to her. Meanwhile, Rogelio persuades Xo to hire his band; Petra gets her husband arrested; and Jane wrestles with how to proceed in her relationship with Michael.
A music producer contacts Xo about recording a demo, but Xo's unaware that Rogelio is behind this. Meanwhile, Jane and Rafael share surprising secrets with one another; Michael comes close to solving his case; and Petra won't make things easy for Rafael.
Xo meets her idol when she attends an awards show with Rogelio, Jane and Alba. Meanwhile, a secret of Petra's is uncovered by Jane and Rafael, leading them to worry about how she really feels regarding the baby.
A hurricane hits town, forcing Jane to stay at the Marbella. Meanwhile, Rogelio comforts Xo when he learns about Alba's condition; Rafael gets his old job back and must make a tough call regarding staff layoffs; and Michael tries to assist Alba quietly.
Jane is torn when she is offered a permanent position at the Catholic high school, even as Rogelio offers her a writing internship at his telenovela. Alba tells Xo to keep the promise she made about Rogelio. Meanwhile, Michael goes against his boss's orders when his suspicions grow that Rafael is involved with Sin Rostro
Jane gets a big break in her career, but it all seems too good to be true, especially when it involves Rogelio. Rafael is stressed about Sin Rostro's connection to the hotel and begins to fear for his family's safety. Meanwhile, Petra's past is quickly catching up with her and she is disheartened when she learns the truth about someone very close to her
Jane and Rafael are eager to know the baby's gender. Though, they experience medical problems, and Jane may miss her graduation. Meanwhile, Alba keeps quiet about something she is humiliated to talk about to her daughter, Xo. Elsewhere, Michael believes he has found out who Sin Rostro is, but he must capture him before he flees.
Michael attempts to convince Jane that Rafael is involved with hiding his father's involvement, which he succeeds as Jane questions her baby's father. Xo and Rogelio are at odds when they are forced to speak with each other. Petra discovers a new way to make Rafael's life more miserable. Meanwhile, Jane questions her future with Rafael when her friends throw her a baby shower.
Jane and Rafael receive exciting news about their baby's health. They resume the topic of moving in together and Rafael surprises Jane. Alba gives bad advice to Jane and Xo. Meanwhile, Petra makes an ally with Rafael when Lachlan attempts to blackmail her to resign her co-owership of the hotel. Also, Michael informs Jane about her favorite author visiting the Marbella.
Jane is feeling distant from Rafael so she focuses on her writing instead, but is stuck with a case of writers block. When Jane runs into Michael he mentions a romance writing workshop, and she thinks she has found the solution. Petra has a solution to finding a musical performer for the Marbella's Calle Ocho celebration, but it forces Rafael to ask Rogelio for help. Rogelio is struggling with his new character as a detective, so he gets the brilliant idea to shadow Michael for real cop experience. Meanwhile, Xo has made a decision about her life with Rogelio which causes a rift between her and Alba
When a crisis with the hotel overwhelms Rafael, Jane becomes concerned that he might not be as hands-on in fatherhood as she expected. Alba is having a difficult time with Xo's living situation which causes a strain between them. Michael helps Rogelio with his relationship with Xo, and in return Rogelio helps Michael come to a realization about Jane. Meanwhile, Petra discovers a big secret that leaves her unsettled
Jane unintentionally ruins Rafael's chances of getting the hotel's liquor license back, but her attempt to help fix it means missing the Villanueva's Easter festivities. Rafael gets information about his birth mother from the private detective he has hired, but doesn't like what he hears. Rogelio's mother, Liliana, comes for a visit but she and Xo do not have the best history. Alba takes a big step in the romance arena, but is shocked when she learns what Edward (guest star Cheech Marin) does for a living. Meanwhile, Petra becomes more convinced about the secret she thinks she has stumbled upon and enlists Michael's help to get confirmation
Jane is desperate to fix things with Rafael and suggests working on a way to help them move past their problems. Xo has been keeping a secret from Rogelio, but when she finally comes clean to him, Rogelio's reaction surprises her. Alba has a flashback of who pushed her down the stairs. Still dealing with the Sin Rostro aftermath, Michael makes an upsetting discovery about who was involved all along. Meanwhile, Petra finds herself in a dire situation leaving her to save herself
Jane is determined to do what's best for the baby, especially after she and Rafael learn that the baby is breech. Xo continues to try to apologize to Rogelio, but faces an uphill battle. Rogelio is offered a big career opportunity that could bring him back to his glory days. Meanwhile, Alba shares what happened the night of her accident and Jane turns to Michael for help in catching Petra in a lie
Jane tells Rafael about her decision to sue him for sole custody of the baby. Petra, after causing tension between her and Jane, tries to fix the issue after Rafael confides in Petra about Jane's decision. Meanwhile, Jane attends her five-year high school reunion, but she confesses that she did not expect what her life would do at the moment. Xo and Rogelio rehearse for their show, but Xo remains confused as why Rogelio is acting odd. Elsewhere, Jane agrees to attend Michael's police force commendation, but sets a few ground rules.
After having false labor, Jane insists that Xo and Rogelio go to Las Vegas to perform their show, but once they are gone the labor turns very real. Xo does everything she can to get back to help Jane, but ends up making Rogelio feel like he's not part of the family. The truth about Michael and Rafael's feelings for each other, and Jane, are put aside to help make Jane's labor easier. With the good news on the birth of Jane's baby, Alba is excited to tell her special friend. Meanwhile, Petra learns some very important information that concerns Rafael, leaving her to decide if she should tell him